Low serotonin can cause anxiety and panic attacks. Because vitamin B6 and iron are required raw materials for making serotonin, low levels of these two nutrients often contribute to anxiety and panic attacks. Serotonin is synthesised from the amino acid tryptophan in a process that relies on the presence of vitamin B6 and iron. Researchers at Okayama University observed the levels of vitamin B6 and iron in patients who visited the emergency room due to severe panic attacks and compared their measurements with a control group of individuals with healthy levels of both. Interestingly, they found that vitamin B6 and iron levels were significantly lower in the group who suffered from the attacks than in the control group. Although further research is required, this is a noteworthy observation.